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PGT-M conditions

This table shows all PGT-M conditions currently approved and awaiting consideration by the HFEA.

Please note that we are updating this database, and some approved conditions may not be displayed. If you are unsure if a condition has been approved or not, please contact pgtm@hfea.gov.uk.

Condition name Status OMIM number Documents
Neurodegeneration with Brain Iron Accumulation 2A (NBIA2A) approved 256600
Neurodegeneration with Brain Iron Accumulation 2B (NBIA2B) approved 610217
Neurodegeneration with Brain Iron Accumulation 3 (NBIA3) approved 606159
Neurodegeneration with Brain Iron Accumulation 4 (NBIA4) approved 614298
Neurodegeneration with Brain Iron Accumulation 5 (NBIA5) approved 300894
Neurodegeneration with Brain Iron Accumulation 6 (NBIA6) approved 615643
Neurodevelopmental Disorder with Progressive Microcephaly Spasticity and Brain Anomalies (NDMSBA) approved 617527
Neurofibromatosis type 1 (NF1) approved 162200
Neurofibromatosis Type 2 (NF2) approved 101000
Neurogenic muscle weakness, Ataxia, Retinitis Pigmentosa (NARP) approved 551500
Neuronal Ceroid Lipofuscinosis Type 3 (Batten disease) (CLN3) approved 204200
Neuronopathy Distal Hereditary Motor, Type 2C (HMN2C) approved 613376
Neuronopathy Distal Hereditary Motor, Type 2D (HMN2D) approved 615575
Neuronopathy Distal Hereditary Motor, Type 5A (HMN5A) approved 600794
Neuronopathy Distal Hereditary Motor, Type 5B (HMN5B) approved 614751
Neuronopathy Distal Hereditary Motor, Type 5C (HMN5C) approved 619112
Neuronopathy Distal Hereditary Motor, Type 7A (HMN7A) approved 158580
Neuronopathy Distal Hereditary Motor, Type 7B (HMN7B) approved 607641
Neuronopathy Distal Hereditary Motor, Type IX (HMN9) approved 617721
Neuronopathy, distal hereditary motor, type VIII (HMN8) approved 600175