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PGT-M conditions

This table shows all PGT-M conditions currently approved and awaiting consideration by the HFEA.

Please note that we are updating this database, and some approved conditions may not be displayed. If you are unsure if a condition has been approved or not, please contact pgtm@hfea.gov.uk.

Condition name Status OMIM number Documents
Mal de Meleda awaiting approval 248300
Malignant Infantile Osteopetrosis approved 259700
Maple Syrup Urine Disorder (MSUD) approved 248600
Marfan Syndrome (MFS) approved 154700
Meckel-Gruber Syndrome Types 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 and 11 approved 249000, 603194, 607361, 611134, 611561, 612284, 267010, 613885, 614209, 614175 and 615397
Medium-Chain Acyl-CoA Dehydrogenase Deficiency approved 201450
Medullary Cystic Kidney Disease 2 (MCKD2) (also known as Autosomal Dominant Tubulointerstitial Kidney Disease due to Uromodulin Mutations (ADTKD-UMOD) approved 603860
Megaloblastic Anemia due to Dihydrofolate Reductase Deficiency (DHFR) approved 613839
MEGDEL syndrome (3-Methylglutaconic Aciduria with Deafness, Encephalopathy, and Leigh-Like Syndrome) approved 614739
Melanoma Pancreatic Cancer Syndrome approved 606719
Melanoma, cutaneous malignant, susceptibility to, 10 (CMM10) approved 615848
Melanoma, cutaneous malignant, susceptibility to, 2 (CMM2) approved 155601
Melanoma, cutaneous malignant, susceptibility to, 3 (CMM3) approved 609048
Melanoma-Astrocytoma Syndrome approved 155755
MELAS (Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like episodes) approved 540000
Melnick Needles Syndrome approved 309350
Menkes disease approved 309400
Mental Retardation, Autosomal Dominant 26; MRD26 approved 615834
Mental Retardation, autosomal recessive 65 approved 618109
Mental Retardation, X-linked, Syndromic 34, caused by NONO gene mutation (MRXS34) approved 300967