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PGT-M conditions

This table shows all PGT-M conditions currently approved and awaiting consideration by the HFEA.

Please note that we are updating this database, and some approved conditions may not be displayed. If you are unsure if a condition has been approved or not, please contact pgtm@hfea.gov.uk.

Download full approved condition list.

Condition name Status OMIM number Documents
Mitochondrial Complex 1 Deficiency caused by mutation in ACAD9 gene approved 611126
Mitochondrial Complex 1 Deficiency, Nuclear type 13 (MC1DN13) approved 618235
Mitochondrial Complex 1 Deficiency, Nuclear type 17 (MC1DN17) approved 618239
MITOCHONDRIAL COMPLEX 1 DEFICIENCY, NUCLEAR TYPE 17 (MC1DN17) awaiting approval 618239
Mitochondrial Complex 1 Deficiency, Nuclear type 23 (MC1DN23) approved 618244
Mitochondrial Complex 1 Deficiency, Nuclear type 26 (MC1DN26) approved 618247
Mitochondrial Complex 1 Deficiency, Nuclear type 28 (MC1DN28) approved OMIM #618249
Mitochondrial Complex 1 Deficiency, Nuclear type 32 (MC1DN32) approved OMIM #618252
Mitochondrial Complex 1 Deficiency, Nuclear type 33 (MC1DN33), approved 618253
Mitochondrial Complex 1 Deficiency, Nuclear type 34 (MC1DN34) approved 618776
Mitochondrial Complex 1 Deficiency, Nuclear type 35 (MC1DN35) approved 619003
Mitochondrial Complex 1 Deficiency, Nuclear type 36 (MC1DN36) approved 619170
Mitochondrial Complex 1 Deficiency, Nuclear type 37 (MC1DN37) approved 619272
Mitochondrial Complex II Deficiency approved 252011
Mitochondrial Complex III Deficiency approved 124000
Mitochondrial Complex IV Deficiency approved 220110
Mitochondrial Complex V (ATP synthase) Deficiency, Nuclear Type 2 (MC5DN2) approved 614052
Mitochondrial Complex V (ATP synthase) Deficiency, Nuclear Type 5 (MC5DN5) approved 618120
Mitochondrial Complex V Deficiency approved 604273
Mitochondrial DNA Depletion Syndrome 13 (MTDPS13) approved 615471