Our National Patient Survey 2024 report is now live. Thank you to all those that shared their experiences. Read our report here.PGT-M conditions
The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.
When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.
If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.
Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.
Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.
| Condition name | Status | OMIM number | Documents |
|---|---|---|---|
| Congenital Disorder of Glycosylation, Type Il (CDG1L) | approved | 608776 | |
| Congenital Disorder of Glycosylation, Type Im (CDG1M) | approved | 610768 | |
| Congenital Disorder of Glycosylation, Type In (CDG1N) | approved | 612015 | |
| Congenital Disorder of Glycosylation, Type Ip (CDG1P) | approved | 613661 | |
| Congenital Disorder of Glycosylation, Type Iq (CDG1Q) | approved | 612379 | |
| Congenital Disorder of Glycosylation, Type Ir (CDG1R) | approved | 614507 | |
| Congenital Disorder of Glycosylation, Type It (CDG1T) | approved | 614921 | |
| Congenital Disorder of Glycosylation, Type Iu (CDG1U) | approved | 615042 | |
| Congenital Disorder of Glycosylation, Type Iw (CDG1W) | approved | 615596 | |
| Congenital Disorder of Glycosylation, Type Ix (CDG1X) | approved | 615597 | |
| Congenital Disorder of Glycosylation, Type Iy (CDG1Y) | approved | 300934 | |
| Congenital Dyserythropoietic Anaemia types 1a, 1b and 2 | approved | 224120, 615631, 224100 | |
| Congenital Fibrosis of the extraocular muscles (CFEOM1 and CFEOM3B) | approved | 135700 | |
| Congenital Heart Defects and Skeletal Malformations Syndrome (CHDSKM) | awaiting consideration | 617602 | |
| Congenital Heart Defects, Multiple Types, 2 (CHTD2) | approved | 614980 | |
| Congenital Heart Defects, Multiple Types, 4 (CHTD4) | approved | 615779 | |
| Congenital Heart Defects, Multiple Types, 5 (CHTD5) | approved | 617912 | |
| Congenital Heart Defects, Multiple Types, 6 (CHTD6), autosomal dominant and autosomal recessive | approved | 613854 | |
| Congenital Heart Defects, Multiple Types, 7 (CHTD7) | approved | 618780 | |
| Congenital Heart Defects, Multiple Types, 8, with or without Heterotaxy (CHTD8) | approved | 619657 | |
